Description
Nandro 250 from Unigen is a broad spectrum steroid with moderate anabolic and reduced androgenic activity. Its main active ingredient is nandrolone decanoate, which is excreted in the body in small quantities. Delivery form – liquid for injection, vial volume 10 ml, dosage 250.
Nandro 250 Junigen is used to effectively build muscle mass, as well as to increase strength and endurance, strengthen bones and increase immunity. The drug is considered a fairly safe steroid, but its high ability to interact with progestin receptors increases the risk of side effects.
The anabolic activity of the steroid is 150% from testosterone, 30% androgenic from testosterone.
Effects of Nandro 250 Unigen
- pronounced accumulation of muscle volumes, up to 10 kg in one stroke;
- the absence of the rollback phenomenon, whereby the increased weight persists even after the cycle is canceled;
- prevention of the appearance of painful sensations in the joints, strengthening of the bone system and ligaments by activating the production of collagen and synovial fluid;
- increased resistance due to an increase in the mass of red blood cells. This leads to a better oxygen supply to the tissues and less acidification;
- increase the individual immunity of an athlete.Side effects after taking a steroid are rare. They are represented by symptoms of virilization, hypercalcemia, menstrual irregularities, inhibition of ovarian function in women, as well as hyperpigmentation of the skin and irritation of the urinary tract in men.
Pharmacodynamic properties:
A synthetic derivative of testosterone with a weakened but enhanced anabolic androgenic effect.
The anabolic effect is manifested by the activation of the repair processes in the epithelium (integumentary and glandular), in the bone and muscle tissue following the stimulation of protein synthesis and structural components of the cells. Increases the completeness of the absorption of amino acids from the small intestine (against the background of a high-protein diet), creating a positive nitrogen balance. It stimulates the production of erythropoietin and activates anabolic processes in the bone marrow, which manifest themselves as an antianemic effect when iron preparations are simultaneously administered. It inhibits the synthesis of gonadotropins and endogenous testosterone. In high doses it inhibits spermatogenesis. It can slow down children’s growth and sexual development.
Violates the synthesis of vitamin K-dependent plasma coagulation factors (II, VII, IX, X) in the liver, changes the plasma lipid profile (increases LDL concentration and decreases HDL content), improves sodium and water reabsorption in the kidneys, which contributes to the formation of peripheral edema. These effects disappear after discontinuation.
Pharmacokinetic properties:
After i / m administration of 100 mg, Cmax is reached in 1-3 weeks. It undergoes hepatic biotransformation with the formation of 17-ketosteroids. It is mainly excreted in the urine (over 90%) and about 6% in the faeces.
Instructions
Treatment of anemia in renal insufficiency (increased hemoglobin level and cell mass), diabetic retinopathy, muscular dystrophy, Werding-Hoffmann spinal amyotrophy, (adjuvant) breast cancer, glomerulonephritis, extensive burns, osteoporosis.
Method of application
The Nandro 250 course lasts quite a long time – from two to two and a half months. Due to the fact that nandrolone is put on ether with a long side chain, its entry into the body is gradual, injections are performed no more than once a week. The optimal weekly dosage of the steroid is from 400 to 600 mg of the active substance (but, of course, the calculation is made purely individually, usually in the ratio of 4 milligrams of the drug per 1 kilogram of body weight). The standard course is long, and you shouldn’t delay it – you’ll get more results with two short-duration cycles and doses than with a powerful one.
How to take Nandro 250 in combination with other steroids:
The combination of nandrolone is a priority, since the course of the drug alone has a number of drawbacks in the form of suppression of hormone production, reduced libido, etc. Usually Nandro 250 is combined with testosterone. Combinations with stanozolol and methandrostenolone are also possible.
Side effects
In women – symptoms of virilization, inhibition of ovarian function, menstrual disorders, hypercalcemia.
In men: in the prepubertal period – symptoms of virilization, idiopathic hyperpigmentation of the skin, slowing or stopping of growth (calcification of the epiphyseal growth zones of the tubular bones); in the post-pubertal period – irritation of the bladder, gynecomastia, priapism; in old age, prostatic hypertrophy and / or carcinoma.
In men and women – the progression of atherosclerosis, peripheral edema, dyspeptic disorders, impaired liver function with jaundice, changes in the number of leukocytes, pain in long bones, hypercoagulation with a tendency to bleeding.
