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Boldenone (Equipoise) is a potent anabolic steroid with the active chemical boldenone undecylenate, first synthesized in the 1950s, was developed exclusively for veterinary needs (from cows to dogs). However, this has not prevented athletes from all over the world from using this drug in bodybuilding and other sports with success, thanks to its beneficial effect on metabolism, stimulating protein synthesis and increasing the number of red blood cells.

On the black market, boldenone undecylenate is known under the following brands:

  • Equilibrium
  • Boldabol
  • Boldball
  • Bold
  • Ganabol
  • Happy

The steroid profile of the drug:

  • Androgenic index: 50
  • Anabolic index: 100
  • Estrogenic activity: low
  • Progestogenic activity: very low
  • Half-life: 2 weeks
  • Liver toxicity: none.
  • Preparation form: injection
  • The withdrawal period of the drug: 4-5 months

The main effects of the drug:

  • Helps to gain mass (in combination with other steroids), accelerates protein synthesis
  • It stimulates the appetite
  • Dry the muscles, make them relief
  • Increases vascularity
  • Improves endurance performance (as a result of accelerating oxygen transport to the muscles)

History of the discovery of Boldenone and pharmaceutical companies

Back in 1949, the Swiss pharmaceutical company Ciba boldenone patented it as a synthetic anabolic steroid. In the early 1950s and 1960s, the company actively conducted scientific experiments looking for boldenone esters and, in the late 1960s, early 1970s, finally managed to create a long-lasting working ester of boldenone undecylenate, which began to be sold under the brand name Parenabol (meaning – drug injection), which has been used medicinally for muscle hypertrophy and the protection of bones from destruction in osteoporosis.

At the end of the 70s boldenone definitively disappeared from the pharmacological market and appeared a few years later, already on the veterinary market (mainly used to increase muscle mass in horses), with the Equipoise brand thanks to the American biopharmaceutical company Squibb, which sold this drug until the end of 1985.

In 1985, the Belgian chemical company Solvay buys boldenone from Squibb and sells it on its behalf until 1995, which is later taken over by another American pharmaceutical company, Wyeth (later transformed into the veterinary company Fort Dodge Animal Health “), which still sells equipoise to America and other countries of the world.

Currently, many generics (drugs that have active ingredients identical to the patented ones) of boldenone undecylenate have appeared on the market, which means that all the patents for the drug have already expired.

Boldenona undesilenate

Boldenone and animals

As you already understood, there are a few trade names for this drug, all of which are united by the active ingredient boldenone undecylenate. So, as we said above, boldenone was previously used exclusively in animal husbandry (to increase appetite and increase the weight of animals):

  • Equipoise (USA) – for horses
  • Ganabol (Colombia) – for cows and other horned pets
  • Venobol (Germany) – for chickens

Ganabol (veterinary boldenone)

Despite this, athletes, especially Westerners, widely use boldenone in their physical training, because this drug has a strong anabolic effect, moderately androgenic and well tolerated by the body.

The connection between boldenone and other anabolic steroids

It is no secret that many anabolic steroids, in their chemical structure and action on the human body, are very similar. Let’s compare the popular anabolic steroids (methandrostenolone, testosterone and nandrolone) with boldenone in more detail.

Boldenone and methane

Once upon a time, many mistakenly believed (even pharmacological specialists!) That boldenone undecylenate (hereinafter referred to as boldenone) is an injectable analogue of the popular steroid – methandrostenolone, due to their similarity in chemical structure.

If we remove the methyl group in seventeenth position from Dianabol and the ether chain in the same position in boldenone, then in both cases these drugs will have identical chemical formulas, it has been this fact, for a long time, that has misled many people.

This is so, but the methyl group in the seventeenth position has a strong effect on the final properties of the drug, changing its spatial structure of the molecule. After the methandrostenolone has passed through the liver 2-3 times! the methyl group in the seventeenth position is cleaved and “methane” is converted to 17-methyl-estradiol and the boldenone molecule, with the same cycle, is converted into weaker estradiol, the whole process of cleavage and transformation takes place under the influence of * aromatase.

* Aromatase is an adrenal enzyme that converts androgens (male sex hormones) into estrogen.

Therefore, the differences will be as follows:

  1. The degree of aromatization (the conversion of testosterone to estradiol, in a substance with estrogenic properties) of boldenone is much lower than that of “methane”
  2. Unlike boldenone, methandrostenolone is unable to activate the androgen receptor file (due to the methyl group)

Methandrostenolone 100 tablets (anabolic steroids)

As you can see, these are not so much the same drugs, or rather they are completely different, and they have only one thing in common: stimulating the appetite, which is why both drugs are so popular during the mass gain period.

Boldenone and testosterone

The boldenone undecylenate molecule also has a similar structure to the testosterone molecule, the only difference is in the presence of an additional double bond (ring A), due to which, boldenone is considered a universal drug, because it is not subject to the action of the enzyme 5-alpha reductase, and this is the human enzyme that is responsible for the conversion of testosterone to dihydrotestosterone (DHT).

5-alpha-reductase is a human enzyme involved in steroidogenesis, i.e. the biological process in which steroids are formed from cholesterol and their further transformation into other steroids.

That is, it turns out that 5-alpha-reductase radically changes the properties of the original substance, but as you read above, it has no effect on boldenone, which is why this drug is considered universal, regardless of who takes it.

The chemical formula of testosterone

The following general links emerge between boldenone and testosterone:

  • Both substances perfectly stimulate the androgen receptor and have it non-genomic activity (an increase in the number of nuclei in existing muscle fibers).

However, even at high doses, boldenone, unlike testosterone, does not affect the production of IGF-1 (insulin-like growth factor) by muscle fibers.

Boldenone and nandrolone

In their effect on the human body, both drugs have the greatest similarity (despite molecular differences), mainly in the time of activation of the androgen receptor and in the tendency to aromatization.

Aromatization in nandrolone, that is, conversion to estradiol, occurs without the participation of the enzyme aromatase

The identical properties of both drugs, rendered to humans, have misled many experts, according to which, nandrolone and boldenone are two interchangeable drugs. However, this is not entirely true, first of all, because nandrolone is converted under the action of the enzyme 5-alpha reductase into dihydrotestosterone, which is in many ways inferior to testosterone in terms of androgen receptor activity in the tissue. muscle, while 5-alpha reductase in boldenone has no effect, which is why boldenone can rightfully be considered a powerful nandrolone steroid.


Nandrolone from Balkan Pharmaceuticals

And, of course, don’t forget that nandrolone, unlike boldenone, is generally devoid of non-genomic activity. But on the other hand, the first drug is more successful in terms of weight gain, mainly due to the active ability to stimulate progesterone receptors (progestin activity). That is why, boldenone is often used with methandriol dipropionate, which allows it to catch up with nandrolone in terms of mass gain.

Quite often, athletes who use nandrolone in their training change it in the second half of the course to boldenone undecylenate, which is gentler on the body, not so much by suppressing the production of endogenous testosterone, this is testosterone, which is produced by the body independently from cholesterol.

Features of the application and other properties of boldenone

When you gain weight

Athletes use boldenone quite successfully during the “mass gain” period, ie when it is important to increase muscle mass without thinking about its quality. However, at first glance, it may seem that the use of this drug for weight gain is not entirely reasonable, because it is not subject to aromatization and does not exhibit progestin activity. That is why when boldenone is taken for the purpose of gaining mass, it is combined with “long acting” testosterone such as enanthate or cypionate.

When using boldenone (equipoise), appetite increases, which of course has a positive effect on weight gain, however, as many have experienced “chemists” known from their practice, in order to achieve a good result, boldenone must be combined with drugs in which the concentration of the active ingredient is 200 mg / ml.

Boldenone for weight gain

Muscle dryness

Many pharmacological experts recommend using boldenone when drying the muscles because it does well.

The almost total absence of aromatization and progestin activity prevents excess water from accumulating in the body.

However, remember the increased appetite over boldenone when using it for drying.

Boldenone for drying muscle mass

Effect of boldenone on resistance

Boldenone affects the number of red blood cells (erythrocytes) – there are more of them, due to the stimulation of one of the kidney hormones – erythropoietin, which increases due to an increase in metabolites 5b.

This property of boldenone, as an increase in the number of red blood cells, is successfully used by athletes of various sports, in particular aerobic orientation, where endurance plays a decisive role. For bodybuilders, this property of boldenone will also be useful, because, with the growth of muscle mass, the capillary network in the muscles also increases and, of course, we must not forget about the veininess, which will be up to par when using this drug, and this is not an irrelevant factor for bodybuilders who perform in competitions.

Boldenone for the development of resistance

How quickly does boldenone take effect?

Due to the heavy and long ether chain, boldenone does not immediately (slowly) affect the body and remains in the blood for about 3-4 weeks. Another downside to boldenone is the fact that 1/3 of the drug doesn’t work – “ballast”.

The obvious disadvantages of boldenone undecylenate prompted pharmacological laboratories to synthesize the substances boldenone acetate and boldenone propionate, which are distinguished by a longer period of action and rapid inclusion in the work. In addition, both substances (boldenone acetate and propionate) are not without drawbacks, as many athletes note, they are very painful, and are not widely used in bodybuilding, which cannot be said of other sports where endurance is the predominant factor. (athletics, skiing, cycling and so on).

What dosages of boldenone should be used?

The optimal dosage is in the range of 300-800mg per week, and for the low dosages of boldenone (300mg) to be effective, it makes sense to combine them with other anabolic steroids. A working dose for an athlete is around 600-800 mg per week.

The long half-life of boldenone (the time during which half of the drug is removed from the body after the first injection, that is, the concentration of ether in the blood is reduced by 2 times) allows you to make injections no more than once a week. However, pharmacological specialists recommend increasing the dose by 1.5-2 times in the first 2 weeks, due to the slow activation of this drug.

You should not inject boldenone more than once a week, in addition to the risk of increased side effects on the body, you can quickly achieve a cumulative effect (enhanced action).

Boldenone undesilenate

For women

To avoid girls with irreparable side effects in the form of virilization (first of all, male-like hair growth and deepening of the voice) after using boldenone, we highly recommend reducing the dosage to 75-100 mg per week and the duration of the course should not exceed 4-5 weeks.

What steroids can boldenone be combined (used) with?

To increase muscle mass, boldenone is combined with injections of Sustanon or testosterone enanthate. Also, you can add oxymetholone to this pack.

For a more pronounced “mass gain” effect, boldenone can also be used with methandriol dipropionate, while due to methandriol’s short half-life of 2-3 days, its injections should be administered at intervals: 2 ml -1 every 2 days or 3 ml – 1 time in 3 days. Additionally, testosterone can also be added to the boldenone-methandriol combination to accelerate weight gain.

For drying muscles, boldenone is usually used together with trenbolone or stanozolol, some combine all three drugs together, which is also acceptable in principle.

More experienced athletes can try the boldenone + testosterone propionate combination to improve muscle quality and relief.

Boldenone (equipoise) work courses and dosages

The duration of the labor course for men is from 8 to 10 weeks, with the optimal dosage of boldenone from 400 to 800 mg per week (1 time), all that is lt; 400 mg is ineffective, and all that is> 800 mg does not lead to the best result. on the contrary, it increases the risk of side effects.

Boldenone work courses

To gain muscle mass, the equipoise is perfectly combined with trenbolone and testosterone (in this case, we reduce the course to 6 weeks, to avoid suppressing the production of our testosterone and be sure to take antiestrogens)

For relief and dryness of the muscles, boldenone is well combined with Anavar and Winstrol

And, of course, do not forget that not only strength training associated with the use of anabolic steroids is involved in the enhanced process of muscle growth, but also elemental nutrition (for drying, for mass), which is also a powerful anabolic factor in increasing muscle mass and strength …

Steroid course for bulking (boldenone + testosterone enanthate)

We present to you one of the most popular, proven and effective “chemistry” beginner courses, for which you need to purchase the following on the “black market”:

  • Provide 200 or 250 mg / ml
  • Testosterone enanthate 250 mg / ml
  • Tamoxifen 10 mg tablets
  • Anastrozole (1 mg / form) or Letrozole (2.5 mg / form)

Thanks to the inclusion of boldenone in the course, we reduce the dosage of testosterone enanthate to minimum values ​​without prejudice to the anabolic effect, moreover this combination allows to reduce the internal conversion of anabolic steroids into estrogens and the androgenic activity of the course.

Tamoxifen, anastrozole, reduces the level of aromatization of anabolic steroids, thus helping to minimize the side effects caused by high levels of estrogen in the blood.

Approximate weight course for expert “chemical athletes”:

  • Week 1 – 8: Equipoise 800 mg / week (for starters, reduce to 400-600 mg)
  • Weeks 1 – 8: Testosterone Enanthate 500mg / week
  • Weeks 1-10: Anastrozole or letrozole as determined by the estradiol test
  • Week 11-13: Tamoxifen 20 mg per day
  • Week 14: Tamoxifen 10 mg per day

Equipoise has low aromatization, so testosterone injections are proportionally less prone, for example, if boldenone is set to 400/600, testosterone is correspondingly 600/800.

Steroid course for muscle relief and dryness (boldenone + testosterone propionate + winstrol)

To complete this course, we need the following pharmacological drugs:

  • Boldenone 200 mg / ml
  • Testosterone Propionate 100mg / ml
  • Winstrol 50mg / ml (or tablets)
  • Anastrozole (1 mg / form) or Letrozole (2.5 mg / form)
  • Tamoxifen – 20 mg tablets

Inclusion in the Winstrol course will provide you with a high quality lean muscle set and it will look like this:

  • Week 1 – 8: Equipoise 800mg / per week
  • Weeks 1 – 8: Testosterone Propionate 100 mg / ml every other day
  • Week 6-10: Winstrol 50 mg / daily (or 10-20 mg daily, in tablets)
  • Weeks 1-10: Anastrozole or letrozole as determined by the estradiol test
  • Week 11-13: Post-course therapy with tamoxifen

Boldenone Course for Muscle Relief

The dosage of testosterone and boldenone can be reduced, and sometimes it should be reduced, if you start having health problems.

Always remember, the higher the dosage value, the greater the chance of side effects on the body.

Side effects of boldenone (equipoise)

Boldenone has no significant effect on the production of its own testosterone, due to resistance to the 5-alpha reductase enzyme, as well as the inability to convert into a powerful androgen – dihydrotestosterone, therefore, as such side effects (prostatic hypertrophy, acne, baldness, growth of body and facial hair, etc.) due to androgenic activity, the balance is obviously not observed with its correct use (only applies to men).

Furthermore, we note that boldenone’s low estrogenic activity file (2 times lower than that of testosterone!), Allows athletes to use in their workouts without the use of any antiestrogens that protect the athlete from gynecomastia, edema and hypertension, at the at the same time, balanced in the athlete’s body, it acts as an aromatase inhibitor, thereby inhibiting the conversion of testosterone to estrogen, so be sure to monitor the level of estradiol (so that it does not slip to zero).

Acne Ongoing Anabolic Steroids

Due to an increase in the level of erythrocytes, the rheological properties of the blood may deteriorate, that is, the hematocrit (the volume of red blood cells, which reflects the ratio of erythrocytes to plasma) will cause it to increase, so it is important to check the hematocrit on the course of boldenone, in case of deviation from the norm, consult a doctor, as a rule, renal or pentoxifylline is prescribed, which will prevent the aggregation (adhesion) of erythrocytes, that is, will not allow the creation of “columns of coins” and their three-dimensional conglomerates in whole blood, thus improving blood rheology.

Some athletes, when using boldenone, report acne on the arms, shoulders, chest and back, which is quite easily eliminated by applying special hygienic lotions and using antimicrobial soaps.

For women, equipoise is one of the safest anabolic steroids, mainly due to its low androgenic activity (the risk of virilization phenomena will be minimal).

Of course, don’t forget the lipid profile: using anabolic steroids increases your bad cholesterol (LDL) level, so make sure you’re using omega-3 fatty acid supplements on a “chemistry” of course, and get tested for hormones.

Opinions on boldenone

If we analyze the reviews on the use of boldenone, it becomes clear that this drug has proved to be very effective, both separately when taken, and in combination with other anabolic steroids.

Athletes note that if you take boldenone in the recommended dosages, there are practically no side effects (except acne), but the anabolic effect is quite noticeable (depending on the combination of the course, muscle mass / muscle relief / endurance gradually increases).

Many trainers recommend using Equipoise as the first anabolic steroid, mainly due to its pronounced anabolic effect on the body and low androgenic effect.

Among the negative aspects of boldenone is rather high price, which prevents many athletes from using it in their workouts.


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1 vial (10 ml), 250 mg / ml