Tamoxifen is one of the best SERM (Selective Estrogen Receptor Modulator) products on the market and a very popular Sopharma product used by athletes who use steroids. Tamox is an antagonist and an agonist at the same time, acting as an estrogen in some parts of the body and an antiestrogen in other parts of the body. What determines its action to protect against gynecomastia and activate the production of its own testosterone by normalizing lipid levels, reducing the possibility of atherosclerotic changes.
You can buy Tamoxifen easily and conveniently in our shop.
Mechanism of action
Tamoxifen citrate is indeed a nonsteroidal estrogen receptor blocker that exhibits strong antiestrogenic properties, but is actually a receptor modulator. Tamoxifen is effective in inhibiting the effective binding of estradiol to estrogen receptors, preventing exposure to a specific receptor by blocking the response to estrogen exposure in DNA. The result is a reduction in the activity of the corresponding genes, which decreases the cell’s response to estrogen. In addition, an estrogen antagonist increases the regulation of producing protein W (TGFb), which prevents the development of cancer cells and also reduces the level of insulin-like growth factor 1 (IGF-1), which reduces the division of all cells, including cancer cells. Tamoxifen further reduces the activity of the PKC enzyme and, depending on the dose,
Buying tamoxifen therefore reduces the chance of developing a number of cancers.
Tamoxifen actually has many methods of application when it comes to steroid cycles for top-tier athletes. Due to its wide range of actions, tamoxifen therapy is mainly used by specific bodybuilders in steroid cycles or later as post cycle therapy. First of all, the action of tamoxifen avoids the side effects of steroids related to estrogen. Tamoxifen blocks the oestrene receptors in breast tissue, preventing the development of gynecomastia (breast development in women).
- Blocks estrogen receptors;
- Normalizes the lipid profile, which reduces the possibility of developing atherosclerosis;
- Reduces the risk of breast cancer by 50%;
- Reduces the risk of osteoporosis (bone fragility);
- Activates the production of LH and FSH, increasing the level of endogenous testosterone and is therefore used as a PCT drug;
- It can be used to combat gynecomastia;
The consumption of this drug is individual and for different uses.
For example, to quickly stop the onset of gynecomastia, it is advisable to take 40 mg of tamoxifen per day until the severity of gynecomastia symptoms subsides.
As a PCT product, Tamoxifen is often used in doses of 20-40 mg per day, depending on the “” severity “” of the steroid cycle for 3-4 weeks against the background of taking chorionic gonadotropin 2000 U every other day ( if gonadotropin was not used in the cycle itself, supporting the work of the testicles).
It is important to clarify that it is not recommended to take tamoxifen in case of steroid consumption such as nandrolone, trenbolone or mibolerone, due to the possible increase in progestin side effects.